The Newark Museum of Art holds major collections of American art, decorative arts, contemporary art, and arts of Asia, Africa, the Americas, and the ancient world. Its extensive collections of American art include works by Hiram Powers, Thomas Cole, John Singer Sargent, Albert Bierstadt, Frederick Church, Childe Hassam, Mary Cassatt, Edward Hopper, Georgia O'Keeffe, Joseph Stella, Tony Smith and Frank Stella.
The Museum's Tibetan art galleries are considered among the best in the world. The collection was purchased from Christian missionaries in the early twentieth century. The Tibetan galleries have an in-situ Buddhist altar that the Dalai Lama has consecrated. In addition to its extensive art collections, the Newark Museum of Art is dedicated to natural science. It includes the Dreyfuss Planetarium and the Victoria Hall of Science which highlights selections from the museum's 70,000 specimen Natural Science Collection.